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It's All a Journey's avatar

Thank you for this. You are a hero in this battle. I wish I had been informed about this in 2006 when I started having children. I wish I had seen your articles then. Sadly, I didn’t wake up until much later after all three of my children were already many vax doses in. I thought I was being a good mom, following the pediatrician’s advice and keeping them “safe”.

I woke up in time not to give them HPV or any further boosters of previous vaccines at least and am grateful at least for that. But all three of them have learning disabilities and not a day goes by that I wonder how that might have turned out differently for them had I kept those hideous jabs away from them. Lots of regret.

I am now, fortunately, in a position as a holistic healthcare practitioner where I can help open other parents’ eyes and point them to the research and work done so that they can educate themselves and not repeat my mistakes.

Anyway, just wanted to thank you for your work and acknowledge your important contribution to this fight. ❤️

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Robin Whittle's avatar

The greater risk for African American children being diagnosed with autism follows a pattern of numerous other disparities between people with brown or black skin, especially far from the equator, with those with white skin. A major component of this is due to lower 25-hydroxyvitamin D levels, due to lower rates of production of vitamin D3 in the skin, due to the melanin absorbing ultraviolet light.

This is easily prevented with proper vitamin D3 supplementation.

Vitamin D3 is produced by the action of short-wavelength, high energy per excited electron, ultraviolet B light, ca. 273 nanometres, at the very top (short wavelength) of the Sun's spectrum at the surface of the Earth. This UV-B breaks a bond in one of the carbon rings of 7-dehydrocholesterol and the resulting molecule reconfigures itself to become vitamin D3 cholecalciferol. The primary or sole role of vitamin D3 is to be hydroxylated, primarily in the liver, so about 1/4 of it goes into the bloodstream as 25-hydroxyvitamin D calcifediol (AKA "calcidiol"). This level (concentration) of circulating 25-hydroxyvitamin D is what is measured in "vitamin D" blood tests. It has a half life of weeks to months and supplies both the kidneys and many types of cell all over the body.

Doctors understand, correctly, that about 20 nanograms per millilitre (ng/mL) = 50 nmol/L is sufficient for the kidneys to perform their role in regulating calcium-phosphate-bone metabolism. Most doctors do not understand that many types of immune cell also need a good supply of 25-hydroxyvitamin D, by diffusion from the bloodstream, and that the immune system can only work properly with 50 ng/mL (125 nmol/L) or more circulating 25-hydroxyvitamin D. Many types of immune cell need this good supply of 25-hydroxyvitamin D to feed their intracrine signaling system, which is entirely within the cell, has nothing to do with hormonal signaling, and is crucial to each individual cell's ability to respond to its changing circumstances.

Consequently, governments and many doctors recommend vitamin D3 supplementation in quantities such as 0.025 milligrams (25 millionths of a gram = 1000 IU) or less. In average weight adults this is roughly enough to attain 20 ng/mL circulating 25-hydroxyvitamin D.

However, for 70 kg (154 lb) body weight without obesity, about 0.125 milligrams (5000 IU) a day is required, over several months, to attain at least the 50 ng/mL circulating 25-hydroxyvitamin D the immune system needs to function properly.

See Chauss et al.'s 2021 (Nobel Prize worthy, I think) elucidation of 25-hydroxyvitamin D -> calcitriol intracrine signaling in Th1 regulatory lymphocytes. They mistakenly called it "autocrine" signaling, which involves receptors on the cell surface. Lack of 25-hydroxyvitamin D causes these cells to remain stuck in their pro-inflammatory startup program, never transitioning to their anti-inflammatory shutdown program, despite detecting the condition which activates the intracrine signaling process which, with sufficient 25-hydroxyvitamin D, will achieve this. This is a dense cell-biology article https:// www.nature.com/articles/s41590-021-01080-3. It may help to refer to my attempt at summarizing its most important elements: https:// aminotheory.com/cv19/icu/#2021-Chauss.

Inflammatory responses involve indiscriminate cell destruction, such as due to eosinophils, which are the suicide bombers of the immune system. People with lower 25-hydroxyvitamin D levels are more likely to have these destructive responses to vaccines, and so are at greater risk of neurological complications such as autism.

There's very little vitamin D3 in food, whether it is fortified with vitamin D3 or the the less effective D2. While UV-B exposure of ideally white skin can produce plenty of vitamin D3, this is not available all year round far from the equator - and it always damages DNA and so raise the risk of skin cancer.

30 degrees or more from the equator, UV-B light ca. 293 nanometres is only naturally available in substantial quantities in the middle of cloud-free summer days, without glass, clothing or sunscreen intervening.

Without proper vitamin D3 supplementation or recent extensive UV-B skin exposure, White Americans typically have 5 to 25 ng/mL circulating 25-hydroxyvitamin D. Those with brown or black skin have even less.

Please see the research cited and discussed regarding the vitamin D compounds and the immune system at: vitamindstopscovid.info/00- evi/.

The impact of circulating 25-hydroxyvitamin D levels well below 50 ng/mL begins before birth (pre-eclampsia, pre-term birth, autism, mental retardation vitamindstopscovid.info/00- evi/#3.2), drives infectious and chronic inflammatory diseases and condemns many to cognitive decline -> dementia in old age (vitamindstopscovid.info/00- evi/#3.3).

"p=0.0019" means that the chance of the observed deviation being observed entirely due to randomness in the data, rather than due to a genuine underlying mechanism, is 0.0019 = 1 in 526.

"p=0.001" means that if there was no actual underlying mechanism causing the observed deviation, that on average 1 in 1000 trials, or sets of similar observations, would show a deviation as strong as that which has been observed, due entirely to the random variation, AKA noise, in the data. So, assuming the p figure is accurate, there is a 99.9% chance that the observed deviation is not due to chance.

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